Recombinant adenoviruses are efficient tools for gene delivery in mammalian cells, widely used in both in vivo and in vitro applications. They infect various cell types with high efficiency, and their transient extrachromosomal state ensures safety without genomic integration. Adenovirus DNA undergoes transcription, allowing high-level gene expression in most mammalian cells. Creative Biogene offers a diverse premade adenovirus collection with full-length ORFs, tags, and reporters for comprehensive gene studies. If your gene of interest is not in our collection, our customized adenoviral service caters to specific project needs, exemplifying our leadership in adenoviral technology.
Advantages of Our Gene-Specific Recombinant Adenoviruses
- Efficient Gene Delivery: Recombinant adenoviruses are highly efficient tools for delivering and expressing genes in mammalian cells.
- Broad Cell Compatibility: Adenoviruses exhibit superior infectivity across a diverse range of cell types, suitable for both in vivo and in vitro applications.
- Safe Non-integrating Technology: Adenovirus DNA remains in a transient extrachromosomal state, ensuring safety by avoiding integration into the host cell's genetic material.
- High-Level Gene Expression: Recombinant adenoviruses enable robust gene expression and achieve high virus titers in various mammalian cells.
- Premade Collection and Customization: Creative Biogene offers an extensive premade adenovirus collection, and our advanced technologies support customization for specific research needs.
The gene-specific adenoviral vectors enable simple and rapid functional studies by efficiently transducing target cells in vitro or in vivo to induce robust transient overexpression. The principle involves cloning full-length ORFs into adenoviral transfer vectors optimized for high gene delivery. By circumventing plasmid cloning and transfection, the ready-to-use adenoviruses accelerate experiments investigating exogenous gene overexpression phenotypes and downstream molecular impacts. We provide powerful customizable tools for diverse functional genomics applications：
- Efficient Transduction: Achieve strong and transient gene overexpression through efficient transduction methods, ensuring robust experimental results.
- Time-Efficient Functional Studies: Expedite functional studies by eliminating the need for time-consuming cloning and transfection processes, allowing researchers to focus on core aspects of their experiments.
- Phenotypic and Signaling Impact: Investigate the influence of exogenous genes on phenotypes and signaling pathways, providing valuable insights into gene function and cellular responses.
- Versatile Functional Genomics Tools: Serve as powerful tools for a wide range of functional genomics applications, offering versatility in studying gene functions across different biological contexts and systems.